Howard Hughes Medical Institute CEO salary and executive pay
Howard Hughes Medical Institute paid its CEO, Erin K O'Shea PhD, $1,721,384 for the fiscal year ending August 2025. That is up $60,746 (3.7%) from the fiscal year ending August 2024. Total revenue on that return was $2,004,784,057, up 13.9% from $1,760,221,928 for the fiscal year ending August 2024. Howard Hughes Medical Institute ranks 4th of 11 disease charities and medical research groups on this site by CEO pay. Howard Hughes Medical Institute has 4 Form 990 returns on record, for fiscal years ending 2022 to 2025.
Last updated from IRS e-file data. EIN 59-0735717, Chevy Chase, MD.
CEO, fiscal year ending August 2025
$1,721,384
Highest-paid person, fiscal year ending August 2025
$2,004,966Donald KochVP & CHIEF INVESTMENT OFFICER
- Total revenue
- $2,004,784,057
- CEO pay vs. peers
- Higher than 21%
Source: Form 990, fiscal year ending August 2025, IRS object ID 202640419349301864.View the filing
Peers: the 330 other organizations on this site with revenue of $500 million to $5 billion. Ranked 259th of 331 by top pay as a share of revenue. Pay is 0.09% of revenue, our calculation from the same return. Revenue is Part I, line 12; peers are compared on their latest full-year returns.
Highest-paid people on the latest return
On the latest return, 18 people were paid more than $500,000, 5 of them more than $1 million.
| Name and title | Total |
|---|---|
| Donald KochVP & CHIEF INVESTMENT OFFICER | $2,004,966 |
| Erin K O'Shea PhD CEO PRESIDENT | $1,721,384 |
| Mark SprolesMANAGING DIRECTOR, PRIVATE MARKETS | $1,244,070 |
| Karen EiflerMANAGING DIRECTOR, PUBLIC MARKETS | $1,196,207 |
| Glen ZwickerMANAGING DIRECTOR & HEAD OF INVESTMENT OPERATIONS | $1,118,524 |
Also paid on the latest return: Heidi E Henning Esq (VP & GENERAL COUNSEL & SECRETARY), $887,510; Richard Axel MD (INVESTIGATOR), $854,925; Leslie B Vosshall PhD (VP & CHIEF SCIENTIFIC OFFICER), $850,327; Blanton Tolbert PhD (VP SCIENCE LEADERSHIP AND CULTURE (THRU 05/25)/LAB HEAD), $833,368; Ronald Vale PhD (SENIOR GROUP LEADER/FORMER VP & EXEC. DIR., JRC), $826,070; Nelson Spruston PhD (VP & EXEC DIR, JANELIA RESEARCH CAMPUS), $715,383; David E Clapham PhD (SENIOR GROUP LEADER/FORMER VP & CHIEF SCIENTIFIC OFFICER), $663,738; Gerald M Rubin PhD (SENIOR GROUP LEADER/FORMER VP & EXEC. DIR., JRC), $661,837; Sean B Carroll PhD (INVESTIGATOR/FORMER VP SCI. & ED. MEDIA GROUP), $655,265; Seth Grossman Esq (VP, CHIEF OPERATING OFFICER & SENIOR ADVISOR TO THE PRESIDENT), $588,161; Lynne Lochte (CHIEF FINANCIAL OFFICER & TREASURER), $534,890; Kristina Heiberger Esq (DEPUTY GENERAL COUNSEL & ASSISTANT SECRETARY), $507,283; Bodo Stern PhD (CHIEF OF STRATEGIC INITIATIVES), $500,810; Natasha Neises (SENIOR DIRECTOR, FINANCIAL PLANNING & ANALYSIS), $339,650; Jeremy Compton (CONTROLLER), $305,482; and 14 more.
CEO pay by year
Each row is the CEO on that year's return.
| Fiscal year ending | Name and title | Total | Revenue | Source |
|---|---|---|---|---|
| Aug 2025 | Erin K O'Shea PhD CEO PRESIDENT | $1,721,384 | $2,004,784,057 | Filing |
| Aug 2024 | Erin K O'Shea PhD CEO PRESIDENT | $1,660,638 | $1,760,221,928 | Filing |
| Aug 2023 | ERIN K O'SHEA PHD CEO PRESIDENT | $1,639,888 | $749,022,788 | Filing |
| Aug 2022 | ERIN K O'SHEA PHD CEO PRESIDENT | $1,548,899 | $2,117,477,557 | Filing |
How this pay was reported
The parts of each total, as reported on the return for the fiscal year ending August 2025.
Source: Form 990, fiscal year ending August 2025, IRS object ID 202640419349301864.View the filing
| Part VII | Schedule J | |||||||
|---|---|---|---|---|---|---|---|---|
| Name and title | From org | Other | Base | Bonus | Other | Deferred | Nontaxable | Total |
| Donald KochVP & CHIEF INVESTMENT OFFICER | $1,928,020 | $76,946 | $1,140,785 | $765,853 | $21,382 | $34,500 | $42,446 | $2,004,966 |
| Erin K O'Shea PhDPRESIDENT | $1,652,120 | $69,264 | $1,622,670 | $0 | $29,450 | $34,500 | $34,764 | $1,721,384 |
| Mark SprolesMANAGING DIRECTOR, PRIVATE MARKETS | $1,207,419 | $36,651 | $605,195 | $576,365 | $25,859 | $34,500 | $2,151 | $1,244,070 |
| Karen EiflerMANAGING DIRECTOR, PUBLIC MARKETS | $1,160,055 | $36,152 | $619,136 | $538,964 | $1,955 | $34,500 | $1,652 | $1,196,207 |
| Glen ZwickerMANAGING DIRECTOR & HEAD OF INVESTMENT OPERATIONS | $1,043,689 | $74,835 | $546,919 | $472,358 | $24,412 | $34,500 | $40,335 | $1,118,524 |
These figures come from Howard Hughes Medical Institute's Form 990 returns, as the IRS publishes them. The methodology page explains how they're chosen. To report an error, email corrections@ceopaycheck.com.
How Howard Hughes Medical Institute compares
Ranked 4th of 11 disease charities and medical research groups by CEO pay.
- Previous in this ranking: 3rd, Scripps Research, $1,859,240
- Next in this ranking: 5th, American Association for Cancer Research, $1,705,978
Closest in revenue among organizations in the same revenue band:
Smithsonian Institution$1,038,055 (highest-paid), fiscal year ending Sep 2025
Chicago Community Trust$685,048 (CEO), fiscal year ending Sep 2025
BAYADA Home Health Care$5,516,084 (CEO), fiscal year ending Dec 2024
AIDS Healthcare Foundation$668,273 (CEO), fiscal year ending Dec 2024
The Nature Conservancy$936,855 (CEO), fiscal year ending Jun 2025
Common questions
Erin K O'Shea PhD (PRESIDENT) was paid $1,721,384 for the fiscal year ending August 2025: $1,652,120 from Howard Hughes Medical Institute and $69,264 in other compensation (Part VII columns D and F).
The highest-paid person on the latest return was Donald Koch (VP & CHIEF INVESTMENT OFFICER), at $2,004,966. That is $283,582 more than the CEO, Erin K O'Shea PhD.
Howard Hughes Medical Institute paid its CEO, Erin K O'Shea PhD, $1,721,384 for the fiscal year ending August 2025. That is up $60,746 (3.7%) from the fiscal year ending August 2024. The earliest return on record is for the fiscal year ending August 2022, when the CEO was ERIN K O'SHEA PHD, paid $1,548,899. By fiscal year end: August 2022, $1,548,899 (ERIN K O'SHEA PHD); August 2023, $1,639,888; August 2024, $1,660,638; August 2025, $1,721,384.
Howard Hughes Medical Institute's return for the fiscal year ending August 2025 reports total expenses of $1,178,202,544 and total revenue of $2,004,784,057 (Part I, lines 18 and 12), so revenue exceeded expenses by $826,581,513. Expenses were $1,152,447,870 for the fiscal year ending August 2024, so they rose 2.2%. The CEO's pay of $1,721,384 equals 0.15% of expenses, our calculation.
From the 4 Form 990 returns Howard Hughes Medical Institute filed with the IRS for fiscal years ending 2022 to 2025. The latest full-year return was filed on February 10, 2026. Schedule J of the fiscal year ending August 2025 return breaks down pay for all 5 people in the pay breakdown above.